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        Nc2Eye

           A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of uveal melanoma (UM)
ncRNA name hsa-miR-224-5p
ncRNA Category miRNA
Disease name uveal melanoma (UM)
Species Homo sapiens
Tissues/Cell_line UM cell line OCM‐1A; human embryonic kidney cell line HEK293T
Methods qPCR, Western blot, transfection, proliferation assay, transwell assay, wound healing assay, luciferase reporter assay
Expression pattern down-regulated
Functional description miR-224-5p was involved in proliferation, invasion, and migration of UM cells via regulation the expression of PIK3R3 and AKT3.
PubMed ID 30825222
Year 2019
Title miR-224-5p inhibits proliferation, migration, and invasion by targeting PIK3R3/AKT3 in uveal melanoma.
Drug-related ncRNA NO

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