ncRNA name | hsa-miR-224-5p |
ncRNA Category | miRNA |
Disease name | uveal melanoma (UM) |
Species | Homo sapiens |
Tissues/Cell_line | UM cell line OCM‐1A; human embryonic kidney cell line HEK293T |
Methods | qPCR, Western blot, transfection, proliferation assay, transwell assay, wound healing assay, luciferase reporter assay |
Expression pattern | down-regulated |
Functional description | miR-224-5p was involved in proliferation, invasion, and migration of UM cells via regulation the expression of PIK3R3 and AKT3. |
PubMed ID | 30825222 |
Year | 2019 |
Title | miR-224-5p inhibits proliferation, migration, and invasion by targeting PIK3R3/AKT3 in uveal melanoma. |
Drug-related ncRNA | NO |
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